INTRACELLULAR OSTEOPONTIN PROTECTS FROM AUTOIMMUNITY-DRIVEN LYMPHOMA DEVELOPMENT INHIBITING TLR9-MYD88-STAT3 SIGNALING

Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling

Abstract Background Autoimmune disorders, including Systemic Lupus Erythematosus (SLE), are associated with increased incidence of hematological malignancies.The matricellular protein osteopontin (OPN) has been linked to SLE pathogenesis, as SLE patients show increased serum levels of OPN and often polymorphisms in its gene.Although widely studied

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Reimagining Research Courses for Scholar Practitioners

This essay shares the ongoing efforts of faculty in one EdD program to embrace applied research methodologies and the shifts made in research coursework to support our doctoral candidates as they explore problems of practice.Framed by third space theory, our redesign work is positioned as the lived experience Shine Shampoo through which we were abl

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